Geneva: The World Health Organization (WHO) has issued a statement on Wednesday clarifying that no conclusive scientific evidence links autism spectrum disorder to acetaminophen (also known as paracetamol) use during pregnancy or childhood vaccines. The announcement comes ahead of the 4th UN High-Level Meeting on Non-Communicable Diseases (NCDs) and mental health, scheduled for September 25, where autism and neurodevelopmental disorders will be a key focus.
Autism, affecting approximately 62 million people globally (1 in 127), remains a complex condition with no definitively established causes. Despite improved awareness and diagnosis, WHO notes that multiple factors may contribute to autism, but extensive research over the past decade has found no consistent association with acetaminophen, commonly known as paracetamol. The organization advises pregnant women to follow their healthcare providers’ guidance and use medications cautiously, particularly in the first trimester.
Addressing longstanding vaccine concerns, WHO reiterated that childhood vaccines do not cause autism. Large-scale, high-quality studies from multiple countries have consistently debunked earlier, flawed claims suggesting a link. Since 1999, WHO’s independent experts have confirmed that vaccines, including those containing thiomersal or aluminum, are safe and unrelated to autism or other developmental disorders.
The WHO’s childhood immunization schedule, adopted globally, has saved an estimated 154 million lives over the past 50 years by protecting against 30 infectious diseases. The Strategic Advisory Group of Experts on Immunization (SAGE) ensures that vaccine recommendations are evidence-based and tailored for maximum protection. Delays or disruptions to these schedules increase the risk of infections, particularly for infants and immunocompromised individuals.
As discussions on autism continue at the UN meeting, WHO emphasized the need for greater understanding of autism’s causes and improved support for autistic individuals and their families. The organization is collaborating with autistic-led groups and others to promote evidence-based care and reduce stigma.
WHO’s statement underscores its commitment to science-driven public health and the dignity of the global autism community.
